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           ExcelApplication xla = new ExcelApplication();
           Workbook WB= xla.Create(FileFormat.Xlsx);
           WB.SavePdf(false, "Path/filename.pdf");

	   Dim oExcelApp As New ExcelApplication()           
       Dim wb As Workbook = oExcelApp.Create(FileFormat.Xlsx)       
       wb.SavePdf(False, "Path/filename.pdf"))